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The Nottingham prognostic index (NPI) is used to determine prognosis following surgery for breast cancer. Its value is calculated using three pathological criteria: the size of the lesion; the number of involved lymph nodes; and the grade of the tumour.
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Calculation
The index is calculated using the formula:
Where:
- S is the size of the index lesion in centimetres
- N is the node status: 0 nodes = 1, 1-3 nodes = 2, >3 nodes = 3
- G is the grade of tumour: Grade I =1, Grade II =2, Grade III =3
Predictive Index Tool Video
Interpretation
Source of the article : Wikipedia
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